FIG 5.
Seroconversion and anti-LPS IgG GMTs elicited by live oral vaccines CVD 1931 and CVD 1944 up to 12 weeks after the last immunization. Mice (n = 24) were immunized orally with 109 CFU in a 200-μl volume three times (on days 0, 28, and 56 [indicated by arrows]), with 1 month between immunizations. Anti-LPS serum IgG titers were measured by ELISA pre- and postimmunization (squares, CVD 1931; triangles, CVD 1944). Titers are expressed as GMTs ± SEM. The percent seroconversion (4-fold increase in titer versus preimmune) is shown.