TABLE 5.

Splenocyte cytokine concentrations in infected and sham-infected mice

Cytokine type	Cytokinee	Mean concn (pg/ml) (×103) ± SD (n = 4)
		Itgβ6−/− mice		WT mice
		Infected	Uninfected	Infected	Uninfected
Th1	IFN-γ	0.384 ± 0.37b	0.124 ± 0.068	0. 922 ± 0.028	0.0516 ± 0.021
	IL-1β	4.3 ± 3.3c,d	0.753 ± 0.44	0.451 ± 0.12	0.429 ± 0.085
	IL-6	10.7 ± 1.9c,d	3.22 ± 1.9	2.15 ± 0.57	3.16 ± 0.29
	IL-12p70	5.11 ± 2.0c,d	2.03 ± 1.1	1.12 ± 0.32	1.01 ± 0.24
	IL-28	4.08 ± 0.54c,d	1.03 ± 0.55	0.561 ± 0.098	0.555 ± 0.12
	TNF-α	10.0 ± 0.23c,d	2.20 ± 1.2	2.01 ± 0.79	1.07 ± 0.34
Th2	IL-2	14.5 ± 0.26c,d	4.09 ± 2.3	2.12 ± 0.43	2.12 ± 0.47
	IL-4	30.9 ± 1.2a,d	16.1 ± 8.5	8.09 ± 2.2	6.99 ± 1.5
	IL-5	12.6 ± 0.11c,d	3.35 ± 1.9	1.87 ± 0.39	1.84 ± 0.32
	IL-10	19.3 ± 0.62c,d	5.79 ± 3.2	3.26 ± 0.71	2.95 ± 0.65
	TGF-β	1.36 ± 0.29c,d	0.478 ± 0.26	0.258 ± 0.058	0.261 ± 0.060
Th17	IL-17	2.53 ± 0.17c,d	0.692 ± 0.38	0.375 ± 0.087	0.359 ± 0.074
	IL-23	0.403 ± 0.05c,d	0.132 ± 0.068	0.0744 ± 0.022	0.0643 ± 0.013

^aP ≤ 0.05 compared to the Itgβ6⁻/− sham-infected group.

^bP ≤ 0.05 compared to the infected WT group.

^cP ≤ 0.001 compared to the Itgβ6^−/− sham-infected group.

^dP ≤ 0.0001 compared to the infected WT group.

^eTNF-α, tumor necrosis factor alpha.