Table 1. Characteristics of include studies in this meta-analysis.
| Study (year) | Ethnicity | Sample size | High myopia | Mean age (cases;control) | Genotyping method | Control | NOS score |
|---|---|---|---|---|---|---|---|
| Qiang, Y (2014) |
Chinese |
1,461 |
≤ −6.00 |
36±14.95;42.5±13.3/31±10.66 |
Taqman |
Free of myopia and
fundus diseases |
7 |
| Zhu, J (a; 2014) |
Chinese |
741 |
≤ −8.00 and AL>26 mm |
39.32±16.94; 71.14±8.52 |
PCR -MassArray |
Normal |
7 |
| Zhu, J (b; 2014) |
Chinese |
234 |
≤ −8.00 and AL>26 mm |
40.96±17.63; 70.17±7.37 |
PCR -MassArray |
Normal |
|
| Jiao, X (a; 2012) |
Chinese |
192 |
≤ −6.00 |
21.80±1.27;
21.68±1.30 |
PCR-DS |
Without refractive error |
8 |
| Jiao, X (b; 2012) |
Chinese |
608 |
≤ −6.00 |
22.19±1.67; 21.66±1.54 |
PCR-DS |
Without refractive error |
|
| Hayashi, H (a; 2011) |
Japanese |
1491 |
AL>26.1 |
57.57±14.75; 74.40±8.37 |
Taqman |
AL<25.0 mm |
7 |
| Hayashi, H (b; 2011) | Japanese | 2054 | AL>26.1 | 57.57±14.75; 38.81±11.83 | Taqman | No history of ocular disease |
AL: axial lengths; DS: directional sequencing; NOS: Newcastle –Ottawa scale