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. 2015 Jul 31;290(38):23039–23049. doi: 10.1074/jbc.M115.654962

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© 2015 by The American Society for Biochemistry and Molecular Biology, Inc.

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FIGURE 4. — Increasing the calcium buffering capacity of the nucleus alters the expression of genes that regulate neuronal architecture. Quantitative RT-PCR analysis of VEGFD, C1q-c, cFOS, and bdnf mRNA levels in uninfected hippocampal neurons and in hippocampal neurons infected with rAAVs driving the expression of the indicated proteins (n = 5–9). Statistically significant differences were determined by one-way ANOVA followed by Tukey's post hoc test. VEGFD: uninfected, PV.NLS-mC, p = 0.03578; mC.NLS, PV.NLS-mC, p = 0.0009283. C1q-c: uninfected, PV.NLS-mC. p = 0.04019; mC.NLS, PV.NLS-mC. p = 0.05287. *, p < 0.05.