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. 2015 Sep 9;89(22):11654–11667. doi: 10.1128/JVI.01815-15

FIG 6.

FIG 6

Viral loads after MERS-CoV challenge in vivo. (A and B) Viral loads, determined as genome copies per nanogram of RNA (A) or infectious virus titers (B) in the lungs of prevaccinated mice after transduction with DPP4-encoding AdV 21 days after boost and challenge with MERS-CoV 25 days after boost. Two independent experiments (n = 4 to 5 per group). Error bars, standard errors of the means (SEM). Dotted line, limit of detection (LOD of qPCR, <1.7 copies/ng RNA). ns, not significant; *, P < 0.05. (C) AdV transduction control mCherry mRNA results (in copies per nanogram of RNA). Error bars, SEM.