FIG 3.

Inhibition of HIV expression by a noncytotoxic dose of MGBG in human macrophages. Human blood monocytes were isolated from 3 healthy donors and allowed to differentiate for 7 days in the culture. The cells were then infected with EGFP-tagged HIV for 6 h and cultured for another week. MGBG was present throughout the process. EGFP⁺ cells were visualized under a fluorescence microscope; all cells in the corresponding fields were also imaged by phase-contrast microscopy.