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Structural integrity of lamins. (A and B) Western blot analysis of structural integrity of lamins A/C and B1 in infected, mock-infected cells (A) and actinomycin D (1 to 5 μg/ml)-treated cells (B). Asterisks indicate disintegration products of lamins. (C) Confocal microscopy sections of infected cells showing distributions of lamin A/C and lamin B1 and accumulation of viral capsids at the nuclear periphery at 24 h p.i. Bar, 5 μm.
