TABLE 4.
Blood chemistry data
| Characteristics | Reference ranges | Study day | Treatment group* | |
| PI-HMF | LE-HMF | |||
| Bicarbonate, mEq/L† | 17–24 | 1 | 23.27 ± 0.45 (59) | 25.05 ± 0.45 (62) |
| 15 | 24.32 ± 0.50 (49) | 25.40 ± 0.39 (58) | ||
| 29 | 25.04 ± 0.43 (40) | 25.54 ± 0.44 (50) | ||
| BUN, mg/dL‡ | 2.5–31.4 | 1 | 11.47 ± 0.78 (56) | 11.89 ± 1.03 (61) |
| 15 | 8.30 ± 1.15 (50) | 11.72 ± 0.68 (58) | ||
| 29 | 5.81 ± 0.38 (40) | 9.31 ± 0.53 (49) | ||
| Prealbumin, mg/dL§ | 7.0–39.0 | 1 | 10.05 ± 0.37 (58) | 9.69 ± 0.33 (54) |
| 15 | 10.11 ± 0.37 (47) | 11.40 ± 0.41 (46) | ||
| 29 | 9.08 ± 0.35 (36) | 10.01 ± 0.35 (37) | ||
| Calcium, mg/dL | 8.0–11.0 | 1 | 10.10 ± 0.08 (56) | 9.93 ± 0.08 (60) |
| 15 | 9.93 ± 0.10 (50) | 9.95 ± 0.07 (57) | ||
| 29 | 9.89 ± 0.09 (40) | 9.82 ± 0.06 (49) | ||
| Phosphorus, mg/dL | 4.2–8.7 | 1 | 6.41 ± 0.17 (54) | 6.20 ± 0.13 (58) |
| 15 | 6.71 ± 0.13 (46) | 6.50 ± 0.12 (56) | ||
| 29 | 6.66 ± 0.10 (40) | 6.46 ± 0.12 (47) | ||
| Magnesium, mg/dL | 1.5–2.1 | 1 | 1.90 ± 0.03 (54) | 1.88 ± 0.02 (59) |
| 15 | 1.80 ± 0.03 (47) | 1.86 ± 0.03 (55) | ||
| 29 | 1.81 ± 0.02 (40) | 1.82 ± 0.03 (46) | ||
| Alkaline phosphatase, U/L | 150–400 | 1 | 443.89 ± 24.50 (55) | 415.40 ± 15.78 (60) |
| 15 | 366.13 ± 21.80 (48) | 332.68 ± 10.87 (57) | ||
| 29 | 335.28 ± 21.84 (40) | 342.36 ± 13.10 (47) | ||
| Sodium, mEq/L | 129–143 | 1 | 137.49 ± 0.49 (61) | 138.42 ± 0.34 (65) |
| 15 | 137.46 ± 0.55 (52) | 137.56 ± 0.29 (59) | ||
| 29 | 139.07 ± 0.41 (41) | 138.70 ± 0.40 (50) | ||
| Potassium, mEq/L | 4.5–7.1 | 1 | 5.39 ± 0.11 (61) | 5.20 ± 0.09 (65) |
| 15 | 5.25 ± 0.09 (52) | 5.23 ± 0.09 (59) | ||
| 29 | 5.25 ± 0.10 (41) | 5.06 ± 0.07 (50) | ||
| Chloride, mEq/L | 100–117 | 1 | 104.16 ± 0.60 (58) | 104.03 ± 0.55 (63) |
| 15 | 104.10 ± 0.72 (49) | 103.88 ± 0.43 (57) | ||
| 29 | 106.00 ± 0.57 (40) | 106.14 ± 0.37 (49) | ||
BUN = blood urea nitrogen; LE-HMF = liquid HMF containing extensively hydrolyzed protein; PI-HMF = powdered intact protein HMF; HC = head circumference.
*Values are mean ± SEM (n).
†Bicarbonate (mEq/L): (SDAY 1) LE-HMF > PI-HMF, P = 0.0419, LSM ± SE: LE-HMF = 24.71 ± 0.56, PI-HMF = 23.33 ± 0.62.
‡BUN (mg/dL): Feeding main effect: LE-HMF > PI-HMF, P = 0.0013, LSM ± SE: LE-HMF = 11.99 ± 0.73, PI-HMF = 8.99 ± 0.83.
§Prealbumin (mg/dL): Feeding main effect: LE-HMF > PI-HMF, P = 0.0049, LSM ± SE: LE-HMF = 10.61 ± 0.35, PI-HMF = 9.32 ± 0.38.