Table 1.
Baseline characteristics.
| Once daily | Twice daily | Total | |
| Children randomized: n | 86 | 87 | 173 |
| Men: n (%) | 41 (48) | 38 (44) | 79 (46) |
| Age (years): median (IQR) [range] | 10.8 (8.7, 14.2) [4.3, 17.6] | 11.2 (9.0, 14.5) [3.8, 17.7] | 11.0 (8.7, 14.3) [3.8, 17.7] |
| Ethnic origin: n (%) | |||
| White | 27 (31) | 17 (20) | 44 (25) |
| Black: African or other | 17 (20) | 29 (33) | 46 (27) |
| Mixed black/white | 5 (6) | 6 (7) | 11 (6) |
| Asian/Thai | 31 (36) | 30 (34) | 61 (35) |
| Other | 6 (7) | 5 (6) | 11 (6) |
| Vertically infected: n (%) | 86 (100) | 84 (97) | 170 (98) |
| CDC stage: n (%) | |||
| N or A | 28 (33) | 39 (45) | 67 (38) |
| B or C | 58 (68) | 48 (55) | 106 (61) |
| Viral load (HIV-1 RNA) ≥50 copies/ml at randomizationa: | |||
| n (%) | 12 (14) | 4 (5) | 16 (9) |
| Median [range] | 120 [51, 91 201] | 135 [57, 270] | 120 [51, 91 201] |
| CD4%: mean (SD) | 32.0 (6.5) | 33.9 (8.6) | 32.9 (7.7) |
| Weight (kg): median (IQR) | 33.3 (24.6, 42.0) | 32.2 (23.9, 43.8) | 33.1 (24.6, 42.6) |
| [Range] | [15.0, 72.5] | [15.6, 68.9] | [15.0, 72.5] |
| Baseline ART first regime: n (%) | 18 (21) | 17 (20) | 35 (20) |
| Exposed to three classes of ART: n (%) | 41 (48) | 46 (53) | 87 (50) |
aAll <50 copies/ml at screening.