TABLE 2.

Genes disrupted in mutants identified in the VPA-sensitivity screen (vma mutants are underlined)

	Group	Genes
1	Secretory pathway	VMA3/CUP5, VPS67/VPS51, SAC2/VPS52, VPS53, LUV1/VPS54, SEC22, PEP12, STP22/VPS23, VPS25, BRO1/ VPS31, VPS66, VMA5, VMA21, VMA16/PPA1, VPH1, PMR1, MNN11, COG6, SAC1, BRE5, RVS167, RVS161,
2.	Transcription complexes	CCR4, TAF14, MOT2, POP2, SNF4
3.	Ubiquitin-dependent proteolytic pathway	MEP2, RPN4, DEF1, UBP3, BRE5,
4.	Mitochondrial function	AFG3, MGM101, MRPL27, MMT2, AIM13/MCS19
5.	Transporters	TRK1, CTR1, GUP1, HXT12, AQR1, TFP3, ATP15, RTC2, SPF1/COD1
6.	Functionally unrelated (other)	IRA1, NPL3, RMD7, SER2, PAC10, KAR3, NCL1, NPL6, BUB1, SPC72, MOG1, FYV6, SDL1, TRP1, NIS1, MKT1, CTK1, TRX3, RPL21A, ERF2, CAT2, GSH1, SLI15, NHP10, KEM1, SCS2, POC4, SLM4, EOS1, NCS2, KRE28, DCG1
7.	Uncharacterized ORFs	YIL090W, YCR061W, YJR018W, YIL166C, YNL120C, YML010W-A