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Human cTnI sequence (A) and ternary structure (B) with HCM-related mutation sites (R21C and R145G) and PKA phosphorylation sites (Ser-23/Ser-24). In the ternary structure, cTnC(1–161) is shown in blue; cTnI(1–172) is in red, and cTnT(236–285) is in yellow. The asterisks indicate the key positions in cTnI.
