In vitro neutralization of ricin toxin by VHH heterodimers and homodimers. Ricin was mixed with serial dilutions of VHH heterodimers (A) JNA8, JNA10, or JNA11 or (B) homodimers JNA2, JNA3, or JNA6 and then applied to Vero cells, as described under “Experimental Procedures.” Cell viability was measured 48 h later. The results represent a representative experiment done in triplicate with each data point indicating mean ± S.D. Each agent was tested at least twice.