Skip to main content
. Author manuscript; available in PMC: 2015 Nov 16.
Published in final edited form as: Ann Intern Med. 2015 Mar 17;162(6):420–428. doi: 10.7326/M14-2082

Table.

TB Classifications Used by the Smear- and Culture-Based Algorithms

TB Classification Smear-Based Algorithm Culture-Based Algorithm
Class A ≥1 sputum smear results were positive. Persons diagnosed with class A TB had to complete TB treatment overseas and would be reclassified as having class B2 TB. ≥1 sputum smear or culture results were positive or TB was clinically diagnosed. Persons diagnosed with class A TB had to complete directly observed therapy for TB overseas and would be reclassified as having class B1 TB.
Class A TB waiver: Persons with class A TB received TB treatment overseas until their sputum smear results became negative and applied for an immigration waiver. A class A TB waiver is rare. Follow-up evaluation after arrival in the United States is mandated for persons with a class A TB waiver. Class A TB waiver: Persons with class A TB received directly observed therapy until their sputum smear and culture results became negative and applied for an immigration waiver. A class A TB waiver is rare. Follow-up evaluation after arrival in the United States is mandated for persons with a class A TB waiver.

Class B1 Chest radiograph suggestive of active TB Chest radiograph, medical history, or examination suggestive of TB

Class B2 Chest radiograph suggestive of inactive TB NA

Class B2 latent TB infection NA Induration of ≥ 10 mm on TST or positive results on an IGRA

No TB Normal chest radiograph Normal chest radiograph

IGRA = interferon-γ release assay; NA = not applicable; TB = tuberculosis; TST = tuberculin skin test.