TABLE I.

Characteristics of Patients Enrolled on Two Prospective Phase II Clinical Trials for Children With Desmoid Tumor

	COG ARST0321	POG 9650
Years of accrual	2004–2009	1997–2001
Period of accrual	63 months	35 months
Eligible subjects	59	27
Age at Dx [median (range)]	13 years (<1–18 years)	10 years (<1–18 years)
Males/females	30/29	20/7
Newly diagnosed	22 (37%)	11 (41%)
Recurrent disease	37 (63%)	16 (59%)
Prior chemotherapy	15/37 (41%)	NA
Prior radiation therapy	6/37 (16%)	NA
Multifocal disease	13/55 (24%); 4 Unk	NA
FHx of FAP	10/50 (20%); 9 Unk	NA

COG, Children’s Oncology Group; POG, Pediatric Oncology Group; FAP, familial adenomatous polyposis; Dx, diagnosis; NA, not available; Unk, unknown.