TABLE I.
Biologic subset | Patients (#) | EFS (95% CI) | OS |
---|---|---|---|
Molecular subtype | |||
ERMS | 305 | 77% (72%, 82%) | 82% (77%, 86%) |
ARMS PAX3 | 85 | 54% (43%, 65%) | 64% (52%, 74%) |
ARMS PAX7 | 23 | 65% (42%, 81%) | 87% (64%, 96%) |
ARMS negative | 21 | 90% (65%, 97%) | 89% (64%, 97%) |
Stage 1 or Stage 2, 3/Group I/II | |||
ARMS PAX3 | 28 | 65% (44%, 80%) | 70% (47%, 85%) |
ARMS PAX7 | 12 | 75% (41%, 91%) | 92% (54%, 99%) |
ARMS negative | 10 | 100% | 100% |
Stage 2, 3/Group III | |||
ERMS | 261 | 77% (71%, 81%) | 82% (77%, 86%) |
ARMS PAX3 | 57 | 49% (36%, 62%) | 61% (47%, 73%) |
ARMS PAX7 | 11 | 55% (23%, 78%) | 82% (45%, 95%) |
ARMS negative | 11 | 82% (45%, 95%) | 80% (41%, 95%) |