Table 1.
Data from the Freezing of Gait (FOG) analysis. Shown on this table are the number of patients with and without FOG (row depicted “Number”) and the number (%) for dichotomous variables or mean scores (+/- SD) of continuous variables for the predictors for those with FOG (column named “FOG”) and without FOG (column named “No FOG”).
| Predictors | FOG | No FOG | Odds ratio | 95% CI | P-value |
|---|---|---|---|---|---|
| # (%) or mean (+/- SD) | # (%) or mean (+/- SD) | ||||
| Number | 82 (16%) | 417 (84%) | |||
| PD Duration | |||||
| <6.8 yrs | 14 (17%) | 232 (56%) | Reference | ||
| 6.8-11.8 | 24 (29%) | 104 (25%) | 3.01 | 1.35-6.72 | 0.007 |
| >11.8 | 44 (54%) | 81 (19%) | 4.91 | 2.29-10.54 | <0.0001 |
| Age | |||||
| < 61 yrs | 17 (21%) | 109 (26%) | Reference | ||
| 61.0-69.2 | 17 (21%) | 103 (25%) | 0.67 | 0.28-1.58 | 0.36 |
| 69.2-74.9 | 20 (24%) | 104 (25%) | 0.42 | 0.17-1.07 | 0.07 |
| >74.9 | 28 (34%) | 101 (24%) | 0.51 | 0.21-1.21 | 0.13 |
| Motor predictors | |||||
| Posture/gait subscore | 7.92 (+/- 4.02) | 4.05 (+/- 2.86) | 1.33 | 1.21-1.46 | <0.0001 |
| Tremor subscore | 1.63 (+/- 2.53) | 2.17 (+/- 2.30) | 0.85 | 0.74-0.97 | 0.02 |
| Non-motor predictors | |||||
| BDI2 | 11.71 (+/- 7.39) | 8.74 (+/- 6.64) | 1.03 | 0.99-1.07 | 0.21 |
| Psychotic symptoms | 28 (34%) | 34 (8%) | 3.02 | 1.41-6.49 | 0.004 |
| Sleep | 43 (52%) | 172 (41%) | 0.96 | 0.53-1.75 | 0.89 |
| MMSE | 27.00 (+/- 3.14) | 28.12 (+/- 2.20) | 1.02 | 0.91-1.15 | 0.71 |
| Genetic predictors | |||||
| APOE 4 | 21 (26%) | 90 (22%) | 1.05 | 0.53-2.09 | 0.9 |
| APOE 2 | 16 (20%) | 73(18%) | 1.05 | 0.51-2.16 | 0.89 |
| CYP2D6*4 | 22 (27%) | 150 (36%) | 0.41 | 0.21-0.80 | 0.009 |
| REP 257 | 34 (42%) | 175 (42%) | 1.16 | 0.62-2.18 | 0.64 |
| REP 261 | 15 (18%) | 51 (12%) | 1.76 | 0.75-4.14 | 0.2 |
| MAPT H1H1 | 53 (65%) | 284 (68%) | 0.61 | 0.33-1.12 | 0.11 |