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Multicycle kinetic measurements of mAb-PfRh4 interactions
Kinetic parameters (ka and kd) and KD values extracted from 5H12-rPfRh4 and 10C9-rPfRh4 sensogram fitted to a global 1:1 interaction model are reported. Maximum resonance values (Rmax) and χ2 values of goodness of fit (<10% Rmax) for the models are also presented. RU, resonance units.
| mAb | ka | kd | Rmax | KD | χ2 |
|---|---|---|---|---|---|
| m−1 s−1 | 1/s | RU | m | ||
| 5H12 | 1.29E+05 | 1.73E−04 | 236 | 1.34E−9 | 2.7 |
| 10C9 | 5.64E+04 | 3.69E−05 | 111 | 4.82E−10 | 2.3 |
