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. 2015 Sep 3;290(42):25497–25511. doi: 10.1074/jbc.M115.681445

FIGURE 3.

FIGURE 3.

In aged mice, ursolic acid and tomatidine do not alter total body weight or the weights of heart, liver, or fat pads. A–F, weight-matched cohorts of 22-month-old male C57BL/6 mice were provided ad libitum access to standard chow (control) or standard chow supplemented with 0.27% ursolic acid or 0.05% tomatidine for 2 months. Each data point represents one mouse, and horizontal bars denote means ± S.E. A, initial total body weights. B, final total body weights. C, heart weights. D, liver weights. E, combined weights of bilateral retroperitoneal fat pads. F, combined weights of bilateral epididymal fat pads. p values were determined with a one-way ANOVA with Dunnett's multiple comparison test. N.S. denotes p > 0.05.