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. 2015 Aug 24;290(42):25670–25685. doi: 10.1074/jbc.M115.660753

TABLE 3.

Summary of mass spectrometry data obtained after preincubation of LdtMt5 and different carbapenems

Enzyme Carbapenem Calculated mass of inhibited species Mass of carbapenem Observed massa
Da Da Da
LdtMt5 None 42,603 42,605
Meropenem 42,986.5 383.5 42,605
Imipenem 42,902.4 299.4 42,605
Doripenem 43,023.1 420.1 42,604
Biapenem 42,953.4 350.4 42,606
Tebipenem 42,986.5 383.5 42,605
N358H/M346W LdtMt5 None 42,681 42,683
Meropenem 43,064.5 383.5 42,684
Imipenem 42,980.4 299.4 42,683
Doripenem 43,101.1 420.1 42,683
Biapenem 43,031.4 350.4 42,683
Tebipenem 43,064.5 383.5 42,684

a Reported masses are those that comprise the largest species in the mass spectrum at 100% abundance.