TABLE 3.
Summary of mass spectrometry data obtained after preincubation of LdtMt5 and different carbapenems
| Enzyme | Carbapenem | Calculated mass of inhibited species | Mass of carbapenem | Observed massa | 
|---|---|---|---|---|
| Da | Da | Da | ||
| LdtMt5 | None | 42,603 | 42,605 | |
| Meropenem | 42,986.5 | 383.5 | 42,605 | |
| Imipenem | 42,902.4 | 299.4 | 42,605 | |
| Doripenem | 43,023.1 | 420.1 | 42,604 | |
| Biapenem | 42,953.4 | 350.4 | 42,606 | |
| Tebipenem | 42,986.5 | 383.5 | 42,605 | |
| N358H/M346W LdtMt5 | None | 42,681 | 42,683 | |
| Meropenem | 43,064.5 | 383.5 | 42,684 | |
| Imipenem | 42,980.4 | 299.4 | 42,683 | |
| Doripenem | 43,101.1 | 420.1 | 42,683 | |
| Biapenem | 43,031.4 | 350.4 | 42,683 | |
| Tebipenem | 43,064.5 | 383.5 | 42,684 | 
a Reported masses are those that comprise the largest species in the mass spectrum at 100% abundance.