TABLE 3.
Enzyme | Carbapenem | Calculated mass of inhibited species | Mass of carbapenem | Observed massa |
---|---|---|---|---|
Da | Da | Da | ||
LdtMt5 | None | 42,603 | 42,605 | |
Meropenem | 42,986.5 | 383.5 | 42,605 | |
Imipenem | 42,902.4 | 299.4 | 42,605 | |
Doripenem | 43,023.1 | 420.1 | 42,604 | |
Biapenem | 42,953.4 | 350.4 | 42,606 | |
Tebipenem | 42,986.5 | 383.5 | 42,605 | |
N358H/M346W LdtMt5 | None | 42,681 | 42,683 | |
Meropenem | 43,064.5 | 383.5 | 42,684 | |
Imipenem | 42,980.4 | 299.4 | 42,683 | |
Doripenem | 43,101.1 | 420.1 | 42,683 | |
Biapenem | 43,031.4 | 350.4 | 42,683 | |
Tebipenem | 43,064.5 | 383.5 | 42,684 |
a Reported masses are those that comprise the largest species in the mass spectrum at 100% abundance.