Table 5.
Variable | Hazard Ratio [95% confidence interval] | P | |
---|---|---|---|
Initial Cox regression model with backwards-stepwise selection* | Clinical subgroup (JDM vs. JPM/JCTM) | 4.8 [1.2, 19.6] | 0.03 |
Illness severity at onset | 5.1 [1.4, 17.9] | 0.01 | |
Age at diagnosis | 1.1 [0.98, 1.3] | 0.09 | |
Final Cox regression model | Clinical subgroup (JDM vs. JPM/JCTM) | 8.6 [2.5, 30.2] | 0.001 |
Illness severity at onset | 5.7 [1.6, 19.5] | 0.006 |
Abbreviations. JDM = juvenile dermatomyositis; JPM = juvenile polymyositis; JCTM = juvenile myositis associated with an underlying connective tissue disease.
Multivariable Cox regression model began with clinical subgroup (JDM vs. JPM/JCTM), illness severity at onset, age at diagnosis, weight loss and delay to diagnosis before backwards-stepwise selection; 308 patients were included in the model.