FIGURE 11.

Modulation of cytokine secretion by cystatin D. A, hybridization of cytokine antibody arrays with conditioned media from HCT116-CST5 and HCT116-Mock cells. Two independent biological samples using equal amounts of conditioned media of the two cell types were used. B, quantification of the down-regulation of six cytokines by cystatin D (mean ± S.E., arbitrary units) obtained using two independent biological samples. C, down-regulation of CX3CL1/fractalkine by cystatin D as shown by a specific ELISA. Data are presented as mean ± S.E. of three independent experiments.