Table 1. Antimicrobial resistance of invasive non Hib strains isolated in Ontario, 2010–2014 (n = 664).
a,e,f serotype | Non-typeable | |||||||||
---|---|---|---|---|---|---|---|---|---|---|
Antibiotic | N | MIC50 | MIC90 | Range | %NS # | N | MIC50 | MIC90 | Range | %NS # |
Amoxicillin-clavulanate | 134 | ≤2 | ≤2 | ≤2–4 | 2.2 | 529 | ≤2 | ≤2 | ≤2–8 | 2.6 |
Ampicillin | 134 | ≤0.12 | 1 | ≤0.012 -- >4 | 6.7 | 530 | 0.25 | 1 | ≤0.12–4 | 26.4 |
Ampicillin-sulbactam | 134 | ≤1 | ≤1 | ≤1 -- >2 | 2.2 | 529 | ≤1 | 2 | ≤1–2 | 7.5 |
Cefaclor | 134 | ≤4 | 8 | ≤4 -- >16 | 3.7 | 524 | ≤4 | 8 | ≤4–8 | 11.4 |
Ceftriaxone | 134 | ≤0.03 | 0.06 | ≤0.03–1 | 0 | 530 | ≤0.03 | ≤0.03 | ≤0.03–0.25 | 0 |
Clarithromycin | 134 | 8 | 16 | ≤0.12–16 | 14.2 | 530 | 8 | 8 | ≤0.12 -- >16 | 30 |
Levofloxacin | 134 | ≤0.03 | ≤0.03 | ≤0.03–1 | 0 | 530 | ≤0.03 | ≤0.03 | ≤0.03 -- >4 | 0.2* |
Meropenem | 134 | ≤0.06 | ≤0.06 | ≤0.06–0.5 | 0 | 530 | ≤0.06 | 0.12 | ≤0.06–0.5 | 0 |
*indicates resistance breakpoints have not been established
#indicates both resistance and intermediate category. Non-susceptible and intermediate (= NS)