TABLE 1.

Structures and binding properties of the GHS-R1a ligands

Structures of the GHS-R1a ligands are described in detail in Refs. 1, 24, 33–38. K_i values were determined in this study from competition binding experiments performed by HTRF-based ligand binding assay on HEK293T cells expressing WT GHS-R1a or its A204E mutant (see “Experimental Procedures”). Values are mean ±S.E. of at least three independent experiments performed in triplicate. ND, not determined.