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Bias factors of GHS-R1a ligands
Data were analyzed using the operational model with ghrelin as the reference ligand as described under “Experimental Procedures.” Quantification of bias was only possible for ghrelin, MK-0677, and JMV 1843. Values are mean ± S.E. of three independent experiments performed in triplicate. Statistical analysis was performed using a two-way unpaired Student's t test. NC means cannot be determined. **, p < 0.01; *, p < 0.05. BF = 10ΔΔlog(τ/KA).
