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. Author manuscript; available in PMC: 2015 Nov 16.
Published in final edited form as: Clin Infect Dis. 2014 May 30;59(5):676–681. doi: 10.1093/cid/ciu397

Table 2.

Lyme disease tests at large commercial laboratories by type and percent positive, in four states, 20081

No. of Tests % of Tests % Positive2
701,006 68 5.8
Two-Tiered Whole Cell ELISA/EIA or C6 ELISA3
Standalone Tests
 IgG Western blot 155,800 15 6.5
 IgM Western blot 155,584 15 10.5
 IgM/IgG Combination 82 <1 -
 Whole Cell ELISA/EIA 3,616 <1 11.4
 C6 peptide ELISA 1,655 <1 -
PCR4 7,637 <1 3.1
CSF Antibody5 3,055 <1 -
Culture 7 <1 0

Total 1,053,445
1

Data aggregated from seven U.S. commercial laboratories. Includes specimen testing data from providers in Connecticut, Maryland, Minnesota, and New York.

2

Phase 1 %positive results are presented from five laboratories. CSF antibody not performed by these laboratories.

3

Positive results for C6 (standalone) not reported.

4

PCR testing of blood, cerebrospinal fluid, and/or synovial fluid.

5

No urine antigen tests were reported for these four states.