(A) Six artificial trabecular bone samples showing different levels of bone loss. (B) Normalized power spectral density (PSD) and linear fit (R2 = 0.90, 0.90, 0.92, 0.92, 0.94, 0.96, respectively, for samples 1-6) of each bone sample. (C) The spectral parameter slope quantified from the power spectrum of each bone sample presented as a function of the mean trabecular thickness (MTT).