Example micro-CT images of femur bones of female rats subject to (A) OVX, (B) Sham, and (C) OVX + ZOL with mean trabecular thickness (MTT) 0.10, 0.22 and 0.26 mm, demonstrating the decrease and increase in MTT for the bones in the OVX and OVX + ZOL groups, respectively, in comparion to the normal controls.