Table 3.
Part-worth utilities, RI, and rankings of attributes in overall sample
Parameter | Attribute levels | Part-worth utility estimate (SE)1 | P-value2 | Overall part-worth utility value3 | RI4 (%) | Rank |
---|---|---|---|---|---|---|
Dosing frequency | Once a day (365 times per year) | −0.461 (0.042) | <0.0001 | 0.92 | 41.6 | 1 |
Once a week (52 times per year) | 0.461 (0.042) | <0.0001 | ||||
Type of delivery system | Multidose prefilled pen | −0.393 (0.042) | <0.0001 | 0.79 | 35.5 | 2 |
Single-use prefilled pen | 0.393 (0.042) | <0.0001 | ||||
Frequency of nausea | 20.4% experience nausea | −0.115 (0.022) | <0.0001 | 0.23 | 10.4 | 3 |
18.0% experience nausea | 0.115 (0.022) | <0.0001 | ||||
Weight change | 2.90 kg weight loss | −0.066 (0.022) | 0.0023 | 0.13 | 5.9 | 4 |
3.61 kg weight loss | 0.066 (0.022) | 0.0023 | ||||
Blood sugar (HbA1c) change | 67.9% at goal | −0.040 (0.015) | 0.0095 | 0.08 | 3.6 | 5 |
68.3% at goal | 0.040 (0.015) | 0.0095 | ||||
Frequency of low blood sugar events (hypoglycemia) | Once every 2 years | −0.033 (0.021) | 0.1283 | 0.07 | 3.0 | 6 |
Once every 3 years | 0.033 (0.021) | 0.1283 |
Notes:
Part-worth utility values provide information on the extent to which participants prefer each level of an attribute and are scaled within each attribute to have a mean of 0. A positive part-worth utility value indicates that the attribute level is preferred, while negative values indicate a preference for other levels of the attribute.
The P-values indicate whether the part-worth utility value differs significantly from 0.
The overall utility values represent the range of utility values within each attribute.
, where total utility value = sum of overall utility values across all attributes.
Abbreviations: HbA1c, hemoglobin A1c; RI, relative importance; SE, standard error.