. 2015 Nov 11;11:2865–2873. doi: 10.2147/NDT.S88968

Table S1.

Comparison of the prevalence of each nonmotor symptom with other studies

	Current study (%)	Martinez- Martin et al¹ (%)	P-value (χ² test)	Chaudhuri et al² (%)	P-value (χ² test)	Gan et al³ (%)	P-value (χ² test)
Dribbling	27.14	41.52	0.026^*	35	0.14	17.70	0.128
Taste/smelling	16.19	28.95	0.028^*	26	0.054	22.20	0.279
Swallowing	29.52	28.38	0.755	23.6	0.433	23.40	0.28
Vomiting	12.38	14.31	0.674	8.1	0.397	8.20	0.358
Constipation	50.95	52.48	0.887	46.7	0.831	64.60	0.036^*
Bowel incontinence	2.86	8.21	0.121	4.9	0.435	0.60	0.312
Bowel emptying incomplete	35.71	29.90	0.367	27.6	0.308	15.20	0.001^*
Urgency	49.52	55.81	0.395	61	0.022^*	31.00	0.006^*
Nocturia	62.86	61.90	0.884	66.7	0.116	61.40	0.84
Pains	22.86	28.76	0.333	27.6	0.225	27.20	0.487
Weight	16.67	18.29	0.852	22	0.25	22.20	0.353
Memory	38.10	44.85	0.315	43.9	0.169	65.80	<0.001^*
Loss of interest	26.19	34.67	0.167	29.3	0.425	48.70	<0.001^*
Hallucinations	13.33	22.52	0.066	19.5	0.143	11.40	0.663
Concentrating	27.14	45.71	0.005^*	37.4	0.03^*	38.00	0.097
Sadness/blues	30.00	50.10	0.004^*	44.7	0.018^*	36.70	0.228
Anxiety	25.71	45.33	0.005^*	39.9	0.011^*	30.40	0.471
Sex drive	24.29	34.17	0.119	29.3	0.073	16.50	0.296
Sex difficulty	23.33	32.43	0.154	24.4	0.166	12.00	0.064
Dizzy	34.76	37.14	0.768	39.8	0.308	16.50	0.004^*
Falling	13.81	28.00	0.015^*	30.9	0.002^*	25.90	0.031^*
Daytime sleepiness	12.86	31.11	0.002^*	28.4	0.005^*	38.60	<0.001^*
Insomnia	37.14	45.71	0.196	40.6	0.414	39.20	0.728
Vivid dreams	39.52	33.90	0.38	30.9	0.31	43.70	0.486
RBD	35.24	35.69	0.883	32.5	0.927	27.80	0.332
Restless legs	25.24	41.71	0.011^*	37.4	0.024^*	20.30	0.419
Swelling	14.29	31.30	0.004^*	30.9	0.001^*	8.20	0.183
Sweating	10.48	29.90	<0.001^*	25.2	0.002^*	28.50	0.001^*
Diplopia	12.86	20.00	0.182	21.9	0.065	5.70	0.096
Delusions	6.19	11.07	0.205	12.3	0.11	12.00	0.132

Notes:

Indicates statistical significance. Adapted with permission from Martinez-Martin P, Schapira AH, Stocchi F, et al. Prevalence of nonmotor symptoms in Parkinson’s disease in an international setting; study using nonmotor symptoms questionnaire in 545 patients. Movement Disorders. 2007;22(11):1623–1629. Published by John Wiley and Sons. Copyright © 2007 Movement Disorder Society.¹ And adapted with permission from Chaudhuri KR, Martinez-Martin P, Schapira AH, et al. International multicenter pilot study of the first comprehensive self-completed nonmotor symptoms questionnaire for Parkinson’s disease: the NMSQuest study. Movement Disorders. 2006;21(7):916–923. Published by John Wiley and Sons. Copyright © 2006 Movement Disorder Society.² And adapted from Journal of Clinical Neuroscience. 2014;21(5). Gan J, Zhou M, Chen W, Liu Z. Non-motor symptoms in Chinese Parkinson’s disease patients. 751–754. With permission from Elsevier. Copyright © 2013 Elsevier Ltd. All rights reserved.³

Abbreviation: RBD, rapid eye movement sleep behavior disorder.