Table 3. Concentration of blood metabolites from 15 to 28 d relative to diet initiation for cows either fed controlled-energy diet (CON, 1.30 Mcal/kg; n = 7) or moderate-energy diet (OVE, 1.60 Mcal/kg; n = 7) during TZD administration.
Values are LSM ± SEM.
| Diet | Day | P-value | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Item | CON | OVE | SEM | 15 | 20 | 25 | 28 | SEM | Diet | TZD |
| During TZD | ||||||||||
| Glucose (mmol/L) | 4.49 | 4.66 | 0.07 | 4.55 c | 4.51 c | 4.65 d | 4.61 c d | 0.06 | 0.16 | 0.10 |
| Insulin (μU/mL) | 26.50 | 44.55 | 7.64 | 27.10 c | 41.57 d | 35.43 c d | 34.90 c d | 8.89 | < 0.01 | 0.10 |
| NEFA (mmol/L) | 0.63 | 0.49 | 0.06 | 0.18 | 0.14 | 0.15 | 0.11 | 0.05 | 0.02 | 0.20 |
| BHBA (mmol/L) | 0.23 | 0.40 | 0.02 | 0.27 a | 0.32 a | 0.37 b | 0.31 a | 0.03 | < 0.01 | 0.04 |
| ADIPOQ (μg/mL) | 35.72 | 30.93 | 1.80 | 34.63 | 33.70 | 30.27 | 34.72 | 2.18 | 0.08 | 0.40 |
a,b Means within a row with different superscripts differ (P ≤ 0.05) for TZD, while c,d the trend differs at (P ≤ 0.10). The Diet × Day interaction was not significantly affected.