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. 2015 Nov 16;10(11):e0142884. doi: 10.1371/journal.pone.0142884

Fig 6. Comparison of PCNA, Caspase-3, and NF-κB in the Renal Tubules and Glomeruli in the HFHSD and CD Groups.

Fig 6

A. A glomerulus in the CD group (PCNA). B. Renal tubules in the CD group (PCNA). C. A Glomerulus in the HFHSD group (PCNA). D. Renal tubules in the HFHSD group (PCNA). E. A glomerulus in the CD group (caspase-3). F. Renal tubules in the CD group (caspase-3). G. A glomerulus in the HFHSD group (caspase-3). H. Renal tubules in the HFHSD group (caspase-3). I. A glomerulus in the CD group (NF-κB). J. Renal tubules in the CD group (NF-κB). K. A glomerulus in the HFHSD group (NF-κB). L. Renal tubules in the HFHSD group (NF-κB). Bar = 50 μm. PCNA-positive cells were located mainly in the renal tubules. There were fewer PCNA-positive cells in the HFHSD group compared with the CD group. Caspase-3 was expressed primarily in the renal tubules. The number of caspase-3-positive cells in the HFHSD group was higher than the number of positive cells in the CD group. NF-κB was expressed primarily in the cytoplasm in the CD group; however, positive nuclear expression was also observed in the HFHSD group. CD = control diet, HFHSD = high-fat/high-sucrose diet.