Table 6. Threshold analysis comparing the costs of HPV DNA testing to actual and hypothetical Pap screening (Functional Limit scenario).

	HPV DNA versus Pap 1		HPV DNA versus Pap 2
	Pap 1	HPV DNA	Pap 2*	HPV DNA
Screening cost reduced to:
Lab cost (US$)	No change	1.00	No change	12.93
Total cost (US$)	No change	3.60	No change	15.54
True cases detected	298	361	373	361
Total cost for screening**	38,915	55,083	69,865	69,320
Cost per true case detected	130.63	152.51	187.52	191.92

* Note that this method is not currently allowed under existing guidelines, but was presented as a hypothetical alternative in the validation study.

** For initial screen plus colposcopic biopsy when indicated. Excludes colposcopic biopsy for VIA because not clinically relevant.