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. Author manuscript; available in PMC: 2016 Dec 1.
Published in final edited form as: Hypertension. 2015 Oct 5;66(6):1108–1115. doi: 10.1161/HYPERTENSIONAHA.115.05831

Table 2.

Effect modifiers influencing blood pressure trajectory level within each group: univariate and multivariable analyses, age 7 to 38 years

Univariate Multivariable*
Risk factor Shift in trajectory per unit change in variable 95% CI p-value Shift in trajectory per unit change in variable 95% CI p-value
Body mass index
Normal group 0.53 0.41, 0.65 <.001 0.50 0.36, 0.63 <.001
High-normal group 0.92 0.78, 1.05 <.001 0.79 0.67, 0.91 <.001
Prehypertensive group 1.09 0.94, 1.24 <.001 1.04 0.89, 1.18 <.001
Hypertensive group 1.62 1.18, 2.07 <.001 1.70 1.25, 2.15 <.001
Average weekly alcohol consumption
Normal group 0.02 −0.03, 0.07 .49 0.01 −0.06, 0.08 .72
High-normal group 0.08 0.03, 0.13 .002 0.02 −0.03, 0.06 .47
Prehypertensive group −0.04 −0.10, 0.03 .30 −0.02 −0.06, 0.03 .49
Hypertensive group 0.00 −0.11, 0.11 .98 0.06 −0.11, 0.23 .47
Number of cigarette per day (in last month)
Normal group 0.05 −0.05, 0.15 .33 0.07 −0.04, 0.18 .19
High-normal group 0.11 0.03, 0.19 .007 0.07 0.00, 0.15 .05
Prehypertensive group 0.01 −0.08, 0.11 .83 0.09 0.01, 0.17 .02
Hypertensive group 0.05 −0.11, 0.22 .52 0.23 −0.07, 0.53 .13
*

Model contains early life factors (maternal hypertension, birthweight, birth order, gender, family history of high blood pressure, breastfeeding, early childhood socioeconomic status) and effect modifiers (body mass index, alcohol consumption, cigarette smoking)