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. Author manuscript; available in PMC: 2016 Nov 1.
Published in final edited form as: Exp Eye Res. 2015 Aug 18;140:124–129. doi: 10.1016/j.exer.2015.08.010

Figure 7. Effect of FA on FN, Coll IV, ZO-1, and COX-2 Protein Levels with Inhibition of PPAR-α activity.

Figure 7

(7A) Representative WB image shows there is no significant difference in protein levels of FN, Coll IV, ZO-1, and COX-2 between cells grown in HG treated with FA alone (HG+FA) and cells grown in HG and treated with FA with MK886 (HG+FA+MK886). (7B) Graphical representation of cumulative WB data. Protein levels of FN, Coll IV, ZO-1, and COX-2 are not significantly altered when FA is treated with a PPAR-α inhibitor, demonstrating that the effects of FA on these proteins are PPAR-α independent in RRECs (HG+FA vs. HG+FA+MK886, p > 0.10).