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. 2014 Dec 7;16(9):1005–1018. doi: 10.1007/s10198-014-0649-6

Table 2.

Time trade-off (TTO) health state utilities (N = 182)

Hepatitis C health states TTO with 10-year time horizon TTO with 1-year time horizon
Mean SD Mean SD
Health states differing by treatment regimen
 A. All-oral regimen (1 tablet per day) 0.80 0.30 0.81 0.29
 B. All-oral regimen (2 tablets per day) 0.80 0.30 0.81 0.29
 C. All-oral regimen (3 tablets per day) 0.79 0.30 0.80 0.29
 D. All-oral regimen (7 tablets per day) 0.79 0.30 0.79 0.29
 E. Oral treatment (7 tablets per day) + weekly injection 0.77 0.30 0.77 0.30
 F. Oral treatment (12 tablets per day) + weekly injection 0.75 0.31 0.76 0.32
 G. Oral treatment (12 tablets per day taken with fatty food) + weekly injection 0.71 0.35 0.72 0.35
 H. Oral treatment (18 tablets per day) + weekly injection 0.71 0.35 0.72 0.33
Health states differing by adverse events
 I. Health state E + mild anemia 0.65 0.36 0.65 0.38
 J. Health state E + severe anemia 0.45 0.42 0.47 0.41
 K. Health state E + flu-like symptoms 0.56 0.39 0.57 0.39
 L. Health state E + mild rash 0.65 0.40 0.66 0.37
 M. Health state E + severe rash 0.30 0.50 0.34 0.47
 N. Health state E + depression 0.31 0.48 0.33 0.48

TTO scores are on a scale anchored with 0 representing dead and 1 representing full health