Skip to main content
. 2014 Dec 7;16(9):1005–1018. doi: 10.1007/s10198-014-0649-6

Table 4.

T tests comparing pairs of health states differing in treatment administration attributes (N = 182)

Comparison Hepatitis C health states TTO with 10-year time horizon TTO with 1-year time horizon
Mean utilitya Mean (SD) difference score P valueb Mean utilitya Mean (SD) difference score P valueb
A vs B A. 1 tablet per day 0.80 0.00 (0.01) 0.32 0.81 0.00 (0.01) 0.32
B. 2 tablets per day 0.80 0.81
A vs C A. 1 tablet per day 0.80 0.00 (0.02) 0.059 0.81 0.00 (0.02) 0.041
C. 3 tablets per day 0.79 0.80
A vs D A. 1 tablet per day 0.80 0.01 (0.04) 0.0036 0.81 0.01 (0.06) 0.0032
D. 7 tablets per day 0.79 0.79
B vs C B. 2 tablets per day 0.80 0.00 (0.01) 0.045 0.81 0.00 (0.02) 0.071
C. 3 tablets per day 0.79 0.80
B vs D B. 2 tablets per day 0.80 0.01 (0.03) 0.0026 0.81 0.01 (0.06) 0.0043
D. 7 tablets per day 0.79 0.79
C vs D C. 3 tablets per day 0.79 0.01 (0.03) 0.0036 0.80 0.01 (0.05) 0.0068
D. 7 tablets per day 0.79 0.79
D vs E D. 7 tablets per day 0.79 0.02 (0.05) <0.0001 0.79 0.02 (0.07) 0.0002
E. 7 tablets per day + weekly injection 0.77 0.77
E vs F E. 7 tablets per day + weekly injection 0.77 0.02 (0.06) 0.0002 0.77 0.02 (0.07) 0.0005
F. 12 tablets per day + weekly injection 0.75 0.76
E vs H E. 7 tablets per day + weekly injection 0.77 0.07 (0.16) <0.0001 0.77 0.05 (0.13) <0.0001
H. 18 tablets per day + weekly injection 0.71 0.72
F vs H F. 12 tablets per day + weekly injection 0.75 0.05 (0.13) <0.0001 0.76 0.04 (0.09) <0.0001
H. 18 tablets per day + weekly injection 0.71 0.72
F vs G F. 12 tablets per day + weekly injection 0.75 0.04 (0.16) 0.0005 0.76 0.04 (0.17) 0.0024
G. 12 tablets per day (taken with fatty food) + weekly injection 0.71 0.72

aTTO scores are on a scale anchored with 0 representing dead and 1 representing full health

b P values are based on t tests comparing two utility means