Table 5.

T tests comparing pairs of health states differing in adverse events (N = 182)

Comparison	Hepatitis C health states	TTO with 10-year time horizon			TTO with 1-year time horizon
		Mean utilitya	Mean (SD) difference score	P valueb	Mean utilitya	Mean (SD) difference score	P valueb
E vs I	E. 7 tablets per day plus injectable medication	0.77	0.12 (0.21)	<0.0001	0.77	0.12 (0.23)	<0.0001
	I. health state E + mild anemia	0.65			0.65
E vs J	E. 7 tablets per day plus injectable medication	0.77	0.32 (0.33)	<0.0001	0.77	0.30 (0.31)	<0.0001
	J. health state E + severe anemia	0.45			0.47
E vs K	E. 7 tablets per day plus injectable medication	0.77	0.21 (0.27)	<0.0001	0.77	0.20 (0.26)	<0.0001
	K. health state E + flu-like symptoms	0.56			0.57
E vs L	E. 7 tablets per day plus injectable medication	0.77	0.13 (0.26)	<0.0001	0.77	0.12 (0.21)	<0.0001
	L. health state E + mild rash	0.65			0.66
E vs M	E. 7 tablets per day plus injectable medication	0.77	0.48 (0.44)	<0.0001	0.77	0.43 (0.41)	<0.0001
	M. health state E + severe rash	0.30			0.34
E vs N	E. 7 tablets per day plus injectable medication	0.77	0.47 (0.42)	<0.0001	0.77	0.45 (0.42)	<0.0001
	N. health state E + depression	0.31			0.33
L vs M	L. health state E + mild rash	0.65	0.35 (0.38)	<0.0001	0.66	0.32 (0.37)	<0.0001
	M. health state E + severe rash	0.30			0.34
I vs J	I. health state E + mild anemia	0.65	0.20 (0.26)	<0.0001	0.65	0.18 (0.22)	<0.0001
	J. health state E + severe anemia	0.45			0.47

^aTTO scores are on a scale anchored with 0 representing dead and 1 representing full health

^b P values are based on t tests comparing two utility means