Table 1.
Characteristics of SLE patients and healthy controls.
| SLE patients (n = 64) | Healthy controls (n = 60) | p value | |
|---|---|---|---|
| Clinical features | |||
| Age (years) | 46.8 ± 15.1 | 41.8 ± 12.6 | 0.801 |
| Sex (% of women) | 87.5 | 90 | 0.84 |
| Systolic blood pressure (mmHg) | 120 ± 18 | 114 ± 12 | 0.63 |
| Diastolic blood pressure (mmHg) | 72 ± 13 | 70 ± 12 | 0.54 |
| Clinical manifestations | |||
| Renal involvement | 23.4 | — | NA |
| Seizure | 6.2 | — | NA |
| Severe headache | 4.6 | — | NA |
| Myositis | 4.6 | — | NA |
| Arthritis | 34.3 | — | NA |
| Malar rash/alopecia | 12.5 | — | NA |
| APS | 18.4 | — | NA |
| Retinal vasculitis | 1.5 | — | NA |
| Anemia | 48.4 | — | NA |
| Lymphopenia | 40 | — | NA |
| Leukopenia | 11 | — | NA |
| Thrombocytopenia | 15.6 | — | NA |
| Laboratory parameters | |||
| Total cholesterol (mg/dL) | 188 ± 75 | 193 ± 27 | 0.57 |
| HDL-cholesterol (mg/dL) | 48 ± 9 | 53 ± 4 | 0.54 |
| LDL-cholesterol | 95 ± 2 | 98 ± 3 | 0.91 |
| Triglycerides (mg/dL) | 49 ± 18 | 54 ± 11 | 0.54 |
| Serum iron (μg/mL) | 91 ± 14 | 98 ± 12 | <0.05 |
| Hemoglobin (g/dL) | 8 ± 2 | 9.4 ± 4 | <0.05 |
| C3 (mg/L) | 82.5 ± 32.1 | 102.5 ± 52 | <0.05 |
| C4 (mg/L) | 13.1 ± 6.7 | 31 ± 12.1 | <0.05 |
| Anti-dsDNA (IU/mL) | 814 ± 461 | 1 ± 0.2 | <0.05 |
| Serum creatinine (mg/dL) | 1.2 ± 0.9 | 0.97 ± 0.2 | <0.05 |
| Serum albumin (g/dL) | 2.8 ± 0.7 | 4.1 ± 0.4 | <0.05 |
| Inflammatory marker | |||
| Erythrocyte sedimentation rate (mm/h) | 58 ± 40 | 10 ± 12 | <0.05 |