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. 2015 Nov 1;142(21):3734–3745. doi: 10.1242/dev.125328

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© 2015. Published by The Company of Biologists Ltd

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Fig. 3. — Neural crest cell migration, cell survival, and proliferation of the palatal mesenchyme are unaffected in Wnt1-Cre;Erk2^fl/fl mice. (A,B) lacZ staining of whole-mount E10.5 Wnt1-Cre;R26R^fl/fl (control) and Wnt1-Cre;Erk2^fl/fl;R26R^fl/fl embryos. (C-F) Active caspase 3 immunostaining (green) of E13.5 and E14.5 control and Wnt1-Cre;Erk2^fl/fl palates. Arrowheads indicate positive signal. (G-J) BrdU staining (green) of E13.5 and E14.5 control and Wnt1-Cre;Erk2^fl/fl palates. (K,L) Quantification of apoptotic and proliferating cells in C-F and G-J, respectively. n=3. Scale bars: 100 µm.