Table 2. Transcription factors predicted to regulate shared target genes of Ox-PAPC and NOTCH1 knockdown in HAECs.
| Factor | Genes | Q-value |
|---|---|---|
| Sin3a | 536 | 1.17 × 10−22 |
| Corest | 375 | 3.78 × 10−12 |
| P300 | 414 | 4.38 × 10−10 |
| Hdac2 | 290 | 2.35 × 10−9 |
| Hdac1 | 240 | 7.39 × 10−4 |
| Ctbp2 | 85 | 2.49 × 10−2 |
| Irf1 | 193 | 6.96 × 10−13 |
| Irf3 | 69 | 1.26 × 10−3 |
| Irf4 | 121 | 4.43 × 10−6 |
| Cebpb | 374 | 4.88 × 10−10 |
| Cebpd | 227 | 1.22 × 10−9 |
| Nfkb | 364 | 4.01 × 10−12 |
| Stat1 | 42 | 1.52 × 10−3 |
| Stat2 | 43 | 1.39 × 10−10 |
| Stat3 | 93 | 6.44 × 10−5 |
| Egr1 | 460 | 8.54 × 10−13 |
| Creb1 | 360 | 5.26 × 10−11 |
| Atf1 | 179 | 1.19 × 10−6 |
| Atf2 | 192 | 3.59 × 10−4 |
| Atf3 | 243 | 1.03 × 10−5 |
| Srebp1 | 89 | 2.45 × 10−4 |
| Tal1 | 110 | 7.00 × 10−4 |
A subset of transcription factors predicted to regulate genes changed by 25%, 1% FDR by 50 µg/ml Ox-PAPC (6 h), and NOTCH1 knockdown are shown. The Genes column shows the number of genes in our list that are regulated by the indicated transcription factor.