Table 3.
Predictive value of baseline circulating endothelin-1 levels on CHD in men and women in the Vara-Skövde cohort
| Men (n = 1350) | Women (n = 1395) | ||||
|---|---|---|---|---|---|
| HR | CI | p | HR | CI | p |
| Crude | |||||
| 0.98 | 0.8–1.2 | 0.818 | 1.64 | 1.2–2.3 | 0.003 |
| Adjusted for age | |||||
| 0.98 | 0.8–1.2 | 0.854 | 1.51 | 1.1–2.1 | 0.015 |
| Adjusted for age, HOMA-IR, apoB/apoA1 and smoking | |||||
| 0.88 | 0.7–1.1 | 0.272 | 1.53 | 1.1–2.1 | 0.024 |
Cox-regression analysing the hazard ratio for CHD during follow-up time for changes of endothelin-1 concentrations with 1 pg/ml
HR hazard ratio, CI confidence interval, ApoB/apoA1 apolipoprotein B/apolipoprotein A1, HOMA-IR homeostatic model assessment of insulin resistance