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. 2015 Nov 14;16:385. doi: 10.1186/s12859-015-0809-4

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© Sorokina et al. 2015

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License(http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver(http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — Conservation of β-oxidation module for non-fatty acid compounds. In addition to fatty acids, the β-oxidation module was found conserved for the transformation of 8 compounds represented in the figure. For the first step, we found 4 reaction variants encoded in different RMS of height 1: three RMS correspond to a dehydrogenation between the alpha and beta carbons but with different acceptors, another corresponds to a coenzyme A ligation. A color code indicates the corresponding substrates. Only molecules marked with an asterisk were also detected by Muto et al. (KEGG Reaction Module RM018)