Fig. 4.

A conserved module for the biosynthesis of aldoximes from amino acids. a This module is made of three chemical transformations encoded by RMS-H2 signatures. It corresponds to the oxidative decarboxylation of an anmino acid to its aldoxime. b The module is conserved in different MetaCyc pathways for five distinct proteinogenic amino acids. Produced aldoximes are precursors of nitrogen-containing secondary metabolites in plants, like cyanogenic glycosides for seed germination and defense, or auxin phytohormones