Table 1.

Set of functions for the Boolean model of gonadal sex determination

UGR, UGR & ! (NR5A1 ∣ WNT4)

CBX2, UGR & ! (NR0B1 & WNT4 & CTNNB1)

GATA4, (UGR ∣ WNT4 ∣ NR5A1 ∣ SRY)

WT1mKTS, (UGR ∣ GATA4)

WT1pKTS, (UGR ∣ GATA4) & ! (WNT4 & CTNNB1)

NR5A1, (UGR ∣ CBX2 ∣ WT1mKTS ∣ GATA4) & ! (NR0B1 & WNT4)

NR0B1, (WT1mKTS ∣ (WNT4 & CTNNB1)) & ! (NR5A1 & SOX9)

SRY, ((NR5A1 & WT1mKTS & CBX2) ∣ (GATA4 & WT1pKTS & CBX2 & NR5A1) ∣ (SOX9 ∣ SRY)) & ! (CTNNB1)

SOX9, ((SOX9 & FGF9) ∣ (SRY ∣ PGD2) ∣ (SRY & CBX2) ∣ (GATA4 & NR5A1 & SRY)) & ! (WNT4 ∣ CTNNB1 ∣ FOXL2)

FGF9, SOX9 & ! WNT4

PGD2, SOX9

DMRT1, (SRY ∣ SOX9) & ! (FOXL2)

DHH, SOX9

DKK1, (SRY ∣ SOX9)

AMH, ((SOX9 & GATA4 & NR5A1) ∣ (SOX9 & NR5A1 & GATA4 & WT1mKTS)) & ! (NR0B1 & CTNNB1)

WNT4, (GATA4 ∣ (CTNNB1 ∣ RSPO1 ∣ NR0B1)) & ! (FGF9 ∣ DKK1)

RSPO1, (WNT4 ∣ CTNNB1) & ! (DKK1)

FOXL2, (WNT4 & CTNNB1) & ! (DMRT1 ∣ SOX9)

CTNNB1, (WNT4 ∣ RSPO1) & ! (SRY ∣ (SOX9 & AMH))