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. 2015 Nov 16;15:903. doi: 10.1186/s12885-015-1924-3

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© Wu et al. 2015

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — RT-PCR analysis of the expression of CD44s and its variants in ampullary adenocarcinoma. Fresh samples from six patients with ampullary adenocarcinoma and corresponding normal duodenal tissues were collected from three patients with stage IB cancer (patients 1, 2, and 4) and three patients with stage IIA cancer (patients 3, 5, and 6). Patients 1, 2, and 3 had no disease recurrence while patients 4, 5, and 6 developed recurrence. a HeLa cells served as a positive control. Expression of CD44s, CD44ν3, CD44ν6, CD44ν7, and CD44ν9 was compared between cancer tissue and normal duodenum. The expression patterns were different between patients without recurrence or those with recurrence