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. 2015 Nov 16;15:903. doi: 10.1186/s12885-015-1924-3

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© Wu et al. 2015

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 4 — Expression of CD44s, CD44ν3-10, CD44ν6-10 and CD44ν3,ν8-10 in ampullary adenocarcinoma. a The expression of CD44s and its variants in ampullary adenocarcinoma and corresponding normal duodenal tissues was determined by RT-PCR. β-actin served as a positive control. The fold-change in CD44 isoform/β-actin was labeled below the band. CD44ν3-10 and CD44ν3,ν8-10 mRNA was low in patients without cancer recurrence and increased in those with cancer recurrence. Fold change of cancer/normal ratio of CD44ν6-10 was increased in those with cancer recurrence. b The cancer/normal ratio of CD44/β-actin expression was correlated with cancer recurrence