Table 2.

Correlation between disease recurrence and CD44s expression in patients with ampullary adenocarcinoma who underwent radical resection

	Extent of CD44s expression		P-value
	Negative or weak (< 25 %)a (n = 53)	Moderate or dense (≥ 25 %)a (n = 41)
Liver metastasis	16 (30 %)	9 (22 %)	0.481
Locoregional recurrence	20 (38 %)	14 (34 %)	1.000
Peritoneal carcinomatosis	7 (13 %)	4 (10 %)	0.754
Bone metastasis	9 (17 %)	1 (2 %)	0.039
Other metastasis b	7 (13 %)	4 (10 %)	0.752
Total a,c	35 (66 %)	25 (61 %)	0.668

^aExcludes three patients who died due to surgical complications and one patient with stage IV disease during surgery

^bIncluding brain, lung, and ovary metastases

^cSome patients developed more than one kind of metastases