Table 2. PSA-associated polymorphisms genotyped and analysed in study cohort.
| SNP | Chr | Pos | Risk allele | RAF | Increase per allele (%) | Candidate gene | Reference |
|---|---|---|---|---|---|---|---|
| rs401681 | 5p15 | 1375087 | C | 0.55 | 7 | CLPTM1L | Gudmundsson et al, 2010 |
| rs10788160 | 10q26 | 123023539 | A | 0.31 | 10.2 | RPL19P16 - FGFR2 | Gudmundsson et al, 2010 |
| rs17632542 | 19q13 | 51361757 | T | 0.91 | 39.1 | KLK3 | Gudmundsson et al, 2010 |
| rs11067228 | 12q24 | 113556980 | A | 0.56 | 8.3 | OSTF1P1-TBX3 | Gudmundsson et al, 2010 |
| rs17178655 | 10q11 | 51231805 | A | 0.23 | NR | MSMB | Xu et al, 2010 |
Abbreviations: candidate gene=nearby gene as reported in the cited literature; Chr=chromosome; Pos=chromosomal location; PSA=prostate-specific antigen. RAF=risk allele frequency; SNP=single-nucleotide polymorphism;
Shown are results for alleles that associate with increased (%) levels of PSA. Data are taken from the original publication (Ref).