Table 4. Univariate associations between SNPs and PCa outcomes under a codominant model (P<0.05 by the 2 df test).
| SNP | Chr | Gene | Minor allele | MAF | HR (95% CI) | P value |
|---|---|---|---|---|---|---|
| Biochemical recurrence | ||||||
| rs13385191 | 2 | C2orf43 | A | 0.27 | 1.36 (1.02–1.81) | 0.03 |
| rs339331 | 6 | RFX6/GPRC6A | C | 0.15 | 1.45 (1.03–2.02) | 0.02 |
| Castrate metastasis | ||||||
| rs13385191 | 2 | C2orf43 | A | 0.27 | 1.28 (1.02–1.60) | 0.02 |
| rs9284813 | 3 | VGLL3 | G | 0.26 | 0.75 (0.57–0.98) | 0.03 |
| rs11067228 | 12 | OSTF1P1 | G | 0.48 | 0.74 (0.60–0.93) | 0.009 |
Abbreviations: Chr=chromosome; CI=confidence intervals; HR=hazard ratios; MAF=minor allele frequency; SNP=single-nucleotide polymorphism.