Table 4.

Multiple regression showing predictors of health-related quality of life in patients with SCD

	Physical functioning		Role limitations due to physical health		Role limitations due to emotional problems		Vitality		Emotional well being		Social functioning		Pain		General health
Predictors	B	P	B	P	B	P	B	P	B	P	B	P	B	P	B	P
(Constant)	76.3		61.7		45.3		50.6		74.6		77.5		77.3		59.6
Gender	−3.1	0.278	−0.2	0.964	1.7	0.714	1.1	0.619	−0.6	0.801	1.9	0.503	4.6	0.126	2.9	0.113
Age	−0.2	0.327	0.2	0.519	0.6	0.020*	0.3	0.036*	0.0	0.772	0.2	0.202	−0.1	0.704	0.0	0.834
University	4.9	0.077	10.9	0.009*	13.9	0.003*	5.3	0.013*	3.7	0.102	2.6	0.359	4.1	0.179	3.4	0.060
Married	−3.8	0.191	−8.4	0.056	−15.7	0.001*	−6.9	0.002*	−5.2	0.029*	−6.1	0.036*	−5.7	0.069	−2.8	0.146
Employed	5.1	0.086	1.9	0.673	0.2	0.960	7.3	0.001*	3.5	0.139	3.9	0.190	6.8	0.036*	1.8	0.347
Obese	−1.5	0.717	−3.7	0.555	3.0	0.667	−2.8	0.366	2.1	0.544	−6.1	0.143	−1.4	0.750	−1.0	0.711
Fever	3.2	0.241	−8.7	0.032*	−5.6	0.212	−6.6	0.001*	−3.0	0.162	−5.2	0.054	−4.2	0.148	−1.9	0.292
Skin redness	−5.7	0.033*	−10.9	0.008*	−5.5	0.226	−2.5	0.220	−1.9	0.382	−3.5	0.203	−2.1	0.472	−4.3	0.016*
Swelling	−8.1	0.003*	−6.0	0.131	−7.1	0.108	−4.2	0.036*	−3.4	0.111	−8.4	0.002*	−14.4	0.001*	−4.3	0.013*
Blood transfusion	−6.7	0.046*	−9.8	0.052	−12.9	0.022*	−1.6	0.524	−0.9	0.726	−7.4	0.026*	−8.3	0.024*	−5.9	0.007*
Family history of anemia	−2.8	0.620	−8.6	0.291	2.4	0.788	−5.2	0.208	−7.0	0.119	−6.2	0.239	−8.8	0.125	−2.1	0.564
Family support	−3.7	0.381	−3.2	0.621	−3.3	0.652	1.1	0.730	−1.1	0.754	−2.1	0.638	−7.6	0.107	−4.0	0.160
Other Chronic disease	−4.0	0.293	−5.5	0.328	−1.0	0.867	−6.7	0.019*	−9.7	0.001*	−10.1	0.008*	−3.7	0.369	−0.7	0.786
Regular exercise	0.0	0.988	4.7	0.239	−1.3	0.764	5.6	0.005*	1.7	0.433	6.1	0.024*	7.5	0.009*	5.2	0.003*
Spleen removed	4.2	0.192	8.1	0.090	11.8	0.027*	0.9	0.716	−5.1	0.048*	−3.1	0.326	2.2	0.514	2.3	0.267
F-value	3.2		3.6		2.8		5.4		3		4.3		5.7		4.1
P-value	0.001		0.001		0.001		0.001		0.001		0.001		0.001		0.001
R Square	0.12		0.13		0.10		0.18		0.11		0.15		0.18		0.15
R	0.35		0.36		0.32		0.42		0.33		0.39		0.43		0.38

* Controlling for other predictors in model, predictor is significant at α = 0.05